In pharmaceutical drug delivery of solid oral dosage forms film coatings are frequently applied. The motivation for coating dosage forms range from cosmetic considerations (colour, gloss), improving the stability (light protection, moisture and gas barrier) and making it easier to swallow the tablet. In addition, functional coatings can be used to modify the drug release behaviour from the dosage form. Depending on the polymers used it is possible either delay the release of the drug (such as in enteric coatings) or use the coating to sustain the release of the drug from the dosage form over extended periods of time.
A tablet coating machine is very effective when it comes to coating the external surface of a tablet using a special thin film of the coating material. The basic principle of coating material is applied to a moving bed of tablets. It also makes use of hot air to remove solvents. The tablets are placed in a closed drum and rotated in an orbital manner by influence from a streamlined plate. The coating medium automatically sprays on tablets during this orbital motion in a method that avoids excess coating.
There are parameters which are to be considered in the coating machine. These parameters include, air capacity, coating composition, the surface area of the tablet and lastly the efficiency of the equipment. All these parameters will be shown in HMI. The required sensors & instruments are used to get the input from the machine to the PLC, to control these parameters to maintain the quality and efficiency.
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